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Oxybenzone excretion stratified by CLDN1 rs893051 variant genotype. An excretion curve is plotted for each individual based on the excretion rate at the measured timepoints. (A–C) Excretion curves of individuals with differing genotypes at CLDN1 rs893051. (A) Individuals homozygous for the minor genotype. (B) Individuals with the heterozygous genotype. (C) Individuals homozygous for the major genotype.

Journal: Environmental and Molecular Mutagenesis

Article Title: Polymorphisms in CLAUDIN1 and SPINK5 Influence Skin Absorption of Pyrene, Pyrimethanil, and Oxybenzone in Human Volunteers

doi: 10.1002/em.70050

Figure Lengend Snippet: Oxybenzone excretion stratified by CLDN1 rs893051 variant genotype. An excretion curve is plotted for each individual based on the excretion rate at the measured timepoints. (A–C) Excretion curves of individuals with differing genotypes at CLDN1 rs893051. (A) Individuals homozygous for the minor genotype. (B) Individuals with the heterozygous genotype. (C) Individuals homozygous for the major genotype.

Article Snippet: The exposure experiment (Rietz Liljedahl et al. ) was conducted with pyrene (MilliporeSigma, Burlington, Massachusetts, USA), pyrimethanil (MilliporeSigma), and oxybenzone (Toronto Research Chemicals, Toronto, Canada) (Table ).

Techniques: Variant Assay

Oxybenzone excretion stratified by SPINK5 rs2303067 variant genotype. An excretion curve is plotted for each individual based on the excretion rate at the measured timepoints. (A–C) Excretion curves of individuals with differing genotypes at SPINK5 rs2303067. (A) Individuals homozygous for the minor genotype. (B) Individuals with the heterozygous genotype. (C) Individuals homozygous for the major genotype.

Journal: Environmental and Molecular Mutagenesis

Article Title: Polymorphisms in CLAUDIN1 and SPINK5 Influence Skin Absorption of Pyrene, Pyrimethanil, and Oxybenzone in Human Volunteers

doi: 10.1002/em.70050

Figure Lengend Snippet: Oxybenzone excretion stratified by SPINK5 rs2303067 variant genotype. An excretion curve is plotted for each individual based on the excretion rate at the measured timepoints. (A–C) Excretion curves of individuals with differing genotypes at SPINK5 rs2303067. (A) Individuals homozygous for the minor genotype. (B) Individuals with the heterozygous genotype. (C) Individuals homozygous for the major genotype.

Article Snippet: The exposure experiment (Rietz Liljedahl et al. ) was conducted with pyrene (MilliporeSigma, Burlington, Massachusetts, USA), pyrimethanil (MilliporeSigma), and oxybenzone (Toronto Research Chemicals, Toronto, Canada) (Table ).

Techniques: Variant Assay